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 Supportive wife comforting husband with TRD during a meeting with a counselor in Roxbury.

What Is Treatment-Resistant Depression?

March 08, 2024

Once you’re diagnosed with a depressive disorder, you look to treatments to help manage symptoms like anxiety, desperation, and lack of energy. But, what will you do if customary antidepressants don't seem to help or make your condition worse? If you have taken two or more treatments and still deal with depression, you might have Treatment-Resistant Depression (TRD). Find more details about this condition and get a better idea if you or someone you love has Treatment-Resistant Depression.

How Are Individuals Diagnosed With Treatment-Resistant Depression In Roxbury?

Treatment-resistant depression applies to individuals with major depressive disorder (MDD) who have taken at least two oral antidepressants to the prescribed dose and duration without success. Although you could detect short-lived improvements in mood, they are typically succeeded by a return of symptoms. You may even discover that your episodes of depression are more prolonged and intense.

If antidepressants fail to help you, you’re not alone. According to one study, between 29% and 46% of those participating didn’t get extended relief from oral antidepressants.

What Are Treatment-resistant depression symptoms?

TRD is a subset of a Major Depressive Disorder. Therefore, the symptoms of treatment-resistant depression are known, but you don’t get relief from traditional antidepressants. These symptoms can include:

  • Persistent sadness or emptiness
  • Lack of interest or pleasure in activities
  • Fluctuations in weight or appetite
  • Sleep difficulties like insomnia or lethargy
  • Negative feelings about oneself.
  • Difficulty concentrating
  • Physical phantom pain in joints
  • Self-harm
  • Ongoing thoughts of death or suicide

It's critical to be aware that the consistency and severity of these symptoms, in spite of treatment, make TRD distinct from other kinds of depression. Also, combatting TRD typically calls for a more involved kind of depression treatment near Roxbury, potentially including a blend of prescriptions and psychotherapy.

SPRAVATO Sanctioned For Treatment-Resistant Depression

SPRAVATO is the first FDA-approved nasal spray to treat individuals age 18 and over with treatment-resistant depression. Esketamine is the active ingredient and is considered to reduce symptoms by impacting specific brain pathways. In a clinical trial, people who were treated with Spravato and an oral antidepressant experienced a more pronounced reduction in depressive symptoms after four weeks than individuals who were given a placebo and an antidepressant.

SPRAVATO is administered under direct observation of medical professionals at a facility certified in the Risk Evaluation and Mitigation Strategy (REMS) program. A comprehensive examination of your medical history is required in advance of use. Potentially severe side effects can arise, including feelings of detachment and sedation, and patients are required to be watched for two hours following treatment.

Get Help For Treatment-resistant Depression In Roxbury At The Counseling Center at Roxbury-Succasunna

Treatment-resistant depression can cause an additional level of anxiety with feelings that things may never improve. However, a new strategy for medication, psychotherapy, and expert care will help you get past TRD. The Counseling Center at Roxbury-Succasunna is standing by to help. We provide a number of specialized services for treatment-resistant depression and are an approved SPRAVATO treatment center. Get help now by calling 862-707-2469 or filling out the following form.